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Women with a breast cancer associated with a BRCA mutation have up to a 40% probability of developing a new primary breast cancer within 10 years following initial diagnosis if they did not receive tamoxifen treatment or have an oophorectomy. The woman's ten-year risk for ovarian cancer is also increased by 6-12% under these conditions.
Hereditary breast–ovarian cancer syndromes ( HBOC) are cancer syndromes that produce higher than normal levels of breast cancer, ovarian cancer and additional cancers in genetically related families (either one individual had both, or several individuals in the pedigree had one or the other disease). It accounts for 90% of the hereditary ...
670.04 Endometritis, postpartum. 671 Venous complications in pregnancy and the puerperium. 671.44 Thrombophlebitis, postpartum. 672 Pyrexia of unknown origin during the puerperium. 673 Obstetrical pulmonary embolism. 674 Other and unspecified complications of the puerperium, not elsewhere.
BRCA2 and BRCA2 ( / ˌbrækəˈtuː / [5]) are human genes and their protein products, respectively. The official symbol (BRCA2, italic for the gene, nonitalic for the protein) and the official name (originally breast cancer 2; currently BRCA2, DNA repair associated) are maintained by the HUGO Gene Nomenclature Committee.
The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries. It is currently in its third revision (ICD-O-3). ICD-10 includes a list of ...
BRCA1 is a human tumor suppressor gene [7] [8] (also known as a caretaker gene) and is responsible for repairing DNA. [9] BRCA1 and BRCA2 are unrelated proteins, [10] but both are normally expressed in the cells of breast and other tissue, where they help repair damaged DNA, or destroy cells if DNA cannot be repaired.
Fibrocystic breast changes is a condition of the breasts where there may be pain, breast cysts, and breast masses. [1] The breasts may be described as "lumpy" or "doughy". [3] Symptoms may worsen during certain parts of the menstrual cycle due to hormonal stimulation. [1] These are normal breast changes, not associated with cancer.
Malignant neoplasm of lip, oral cavity, and pharynx (140–149) 140 Malignant neoplasm of lip. 141 Malignant neoplasm of tongue. 142 Malignant neoplasm of major salivary glands. 143 Malignant neoplasm of gum. 144 Malignant neoplasm of floor of mouth. 145 Malignant neoplasm of other and unspecified parts of mouth.