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Hemoglobin (haemoglobin, [a] Hb or Hgb) is a protein containing iron that facilitates the transportation of oxygen in red blood cells. Almost all vertebrates contain hemoglobin, [ 3 ] with the sole exception of the fish family Channichthyidae . [ 4 ]
A:Normal red blood cells are shown flowing freely in a blood vessel on the top of the diagram. The inset image shows a cross-section of a normal red blood cell with normal hemoglobin. B:Demonstrates abnormal, sickled red blood cells blocking blood flow in a blood vessel (vaso-occlusive crisis). The inset image shows a cross-section of a sickle ...
Molecular structure diagrams used in drug-related pharmacology articles should be created using a molecule editor program, such as ChemDraw, ChemSketch, or ISIS/Draw (ChemDraw and Isis/draw are commercial software packages, ChemSketch is freeware.
Hemoglobin variants occur when there are mutations in specific genes that code for the protein chains, known as globins, which make up the hemoglobin molecule. This leads to amino acid substitutions in the hemoglobin molecule that
Images should be drawn with a molecule editor, never freehand; ACS settings should be used for both structures and reaction schemes. These settings are normally available as templates in chemical drawing programs. Use sans-serif fonts like Arial. Indexes used for labelling must be superscripted: R 1-CH 2-R 2 (not R 1-CH 2-R 2)
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First thirty amino acid of normal Hb (on top) and of HbE (down). Hemoglobin E disease results when the offspring inherits the gene for HbE from both parents. At birth, babies homozygous for the hemoglobin E allele do not present symptoms because they still have HbF (fetal hemoglobin). In the first months of life, fetal hemoglobin disappears and ...
Haemoglobin (Hb) Myoglobin (Mb) Neuroglobin: a myoglobin-like haemprotein expressed in vertebrate brain and retina, where it is involved in neuroprotection from damage due to hypoxia or ischemia. [11] Neuroglobin belongs to a branch of the globin family that diverged early in evolution. Cytoglobin: an oxygen sensor expressed in multiple tissues ...
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