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Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
The elimination half-life of DHT in the body (53 minutes) is longer than that of testosterone (34 minutes), and this may account for some of the difference in their potency. [51] A study of transdermal (patches) DHT and testosterone treatment reported terminal half-lives of 2.83 hours and 1.29 hours, respectively. [52]
Conversely, “with too much testosterone, women often have acne, too much hair on the body, hair loss on the head, high blood pressure, elevated cholesterol, skipped cycles, or problems ...
Estimates based on most recent data suggest that each year there are 841,000 new liver cancer diagnoses and 782,000 deaths across the globe. [55] Liver cancer is the most common cancer in Egypt, the Gambia, Guinea, Mongolia, Cambodia, and Vietnam. [55] In terms of gender breakdown, globally liver cancer is more common in men than in women. [43 ...
“Although most people think of testosterone in terms of sexual function, this male hormone has many functions. It is true that low testosterone will lead to lower sexual desire and possibly ...
High levels of testosterone are also achieved with a 60 mg dose of oral testosterone in men with liver cirrhosis. [2] These findings are attributed to induction of liver enzymes by testosterone and consequent activation of its own metabolism. [2] [27] Substitution dosages of oral testosterone in men are in the range of 400 to 800 mg/day.
Testosterone therapy for patients with late-onset hypogonadism, in addition to increasing risk of cardiovascular disease and prostate cancer, may exacerbate the risk factors associated with benign prostatic hyperplasia, a condition that involves the noncancerous enlargement of the prostate gland, which can lead to urinary symptoms.
Testosterone and the cardiovascular system are the effects that the male hormone testosterone has on the cardiovascular system. The predominant androgen in men, testosterone, has shown to substantially decline throughout the aging process. [1] [2] The decline in both serum and total testosterone with age have been linked to several disease ...