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Clockwise from top right: Amoeba proteus, Actinophrys sol, Acanthamoeba sp., Nuclearia thermophila., Euglypha acanthophora, neutrophil ingesting bacteria. An amoeba (/ ə ˈ m iː b ə /; less commonly spelled ameba or amœba; pl.: amoebas (less commonly, amebas) or amoebae (amebae) / ə ˈ m iː b i /), [1] often called an amoeboid, is a type of cell or unicellular organism with the ability ...
A petri dish of Dictyostelium.. When food (normally bacteria) is readily available dictyostelids behave as individual amoebae, which feed and divide normally. However, when the food supply is exhausted, they aggregate to form a multicellular assembly, called a pseudoplasmodium, grex, or slug (not to be confused with the gastropod mollusc called a slug).
In molecular biology, protein aggregation is a phenomenon in which intrinsically-disordered or mis-folded proteins aggregate (i.e., accumulate and clump together) either intra- or extracellularly. [1] [2] Protein aggregates have been implicated in a wide variety of diseases known as amyloidoses, including ALS, Alzheimer's, Parkinson's and prion ...
Life cycle. Dictyostelium discoideum is a species of soil-dwelling amoeba belonging to the phylum Amoebozoa, infraphylum Mycetozoa.Commonly referred to as slime mold, D. discoideum is a eukaryote that transitions from a collection of unicellular amoebae into a multicellular slug and then into a fruiting body within its lifetime.
During the aggregation phase of their life cycle, Dictyostelium discoideum amoebae communicate with each other using traveling waves of cyclic AMP. [51] [52] [53] There is an amplification of cyclic AMP when they aggregate. [54] Pre-stalk cells move toward cyclic AMP, but pre-spore cells ignore the signal. [55]
Most of its life, this haploid social amoeba undergoes a vegetative cycle, preying upon bacteria in the soil, and periodically dividing mitotically. When food is scarce, either the sexual cycle or the social cycle begins. Under the social cycle, amoebae aggregate in response to cAMP by the thousands, and form a motile slug, which moves towards ...
When the amoebae are stressed, typically by a shortage of food, they form a grex. According to species and circumstances, details of the shape of the grex and how it may form will vary but typically the stressed amoebae first produce pheromones that stimulate the flock to vertically assemble in a column. When the column of aggregated cells ...
All species of animals, land plants and most fungi are multicellular, as are many algae, whereas a few organisms are partially uni- and partially multicellular, like slime molds and social amoebae such as the genus Dictyostelium. [2] [3] Multicellular organisms arise in various ways, for example by cell division or by aggregation of many single ...