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Saline solution normally contains 0.9% sodium chloride. This article walks you through application instructions based on the intended use.
Saline solution for irrigation. Normal saline (NSS, NS or N/S) is the commonly used phrase for a solution of 0.90% w/v of NaCl, 308 mOsm/L or 9.0 g per liter. Less commonly, this solution is referred to as physiological saline or isotonic saline (because it is approximately isotonic to blood serum, which makes it a physiologically normal solution).
A retrospective analysis of wound cleanser clinical efficacy and cost-effectiveness focused on polyhexamethylene biguanide solution, Ringer's solution or saline in 112 venous leg ulcer patients. [31] The study group received the polyhexamethylene biguanide solution (n=59) and the control group received either Ringer's solution or saline (n=53).
The dressing should be changed and the wound irrigated with normal saline at least twice each day. [4] In addition, it is recommended to administer an antibiotic active against staphylococci and streptococci, preferably vancomycin when there is a risk of methicillin-resistant Staphylococcus aureus . [ 4 ]
For these purposes PVP-I has been formulated at concentrations of 7.5–10.0% in solution, spray, surgical scrub, ointment, and swab dosage forms; however, use of 10% povidone-iodine though recommended, is infrequently used, as it is poorly accepted by health care workers and is excessively slow to dry.
Saline instillation helps maintain lung expansion during the lavage process, preventing atelectasis (collapse of lung tissue). The total volume of saline used can vary but typically ranges from 15 to 20 liters per lung, administered in aliquots of 500 to 1000 ml. Exogenous surfactant may be administered to help restore normal lung function ...
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