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Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. [1] These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts .
Squamous-cell lung carcinoma is one of the tumor types with the highest number of mutations since smoking, the main driver of the disease, is a strong mutagenic factor. [5] Inactivating mutations in lung SCC affect many tumor suppressor genes such as TP53 (mutated in 81% of cases), MLL2 (20%), CDKN2A (15%), KEAP1 (12%) and PTEN (8%).
Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor.
Mucoepidermoid carcinoma (MEC) [1] is the most common type of minor salivary gland malignancy in adults. Mucoepidermoid carcinoma can also be found in other organs, such as bronchi, lacrimal sac, [2] and thyroid gland. Mucicarmine staining is one stain used by pathologist for detection. [3]
The incidence of lung cancer is highly correlated with smoking. Tobacco smoking is associated with many forms of cancer, [20] and causes 80% of lung cancer. [21] Decades of research has demonstrated the link between tobacco use and cancer in the lung, larynx, head, neck, stomach, bladder, kidney, esophagus and pancreas. [22]
Lewis lung carcinoma is a hypermutated Kras/Nras–mutant cancer with extensive regional mutation clusters in its genome. A tumor that spontaneously developed as an epidermoid carcinoma in the lung of a C57BL mouse .
Lung tumor; A chest X-ray showing a tumor in the lung (marked by arrow) Specialty: Oncology Pulmonology: ... Lung cancer: Causes: Smoking Radon gas Asbestos Air ...
Pulmonary carcinoid tumour is a neuroendocrine tumour of the lung. [1] There are two types: ... Lung carcinoids (cancer.org) This page was last edited on 2 October ...
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