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The craniofacial complex begins its progress in the fourth week of development, and results from neural crest cells migrating to form and fuse the facial primordia. [9] [10] Failures or deviations in this process result in craniofacial clefts, either CL or CP. [6] The range of variation in phenotype aligns with ancestry.
A bifid nose (also known as cleft nose) is an uncommon congenital malformation which is characterized by the presence of a cleft between the two nostrils of the nose. [1] It is the result of a disturbance during embryological nose development. [2] It is part of the Tessier classification for craniofacial clefts. [3]
Cleft lip and palate occurs in about 1 to 2 per 1000 births in the developed world. [2] Cleft lip is about twice as common in males as females, while cleft palate without cleft lip is more common in females. [2] In 2017, it resulted in about 3,800 deaths globally, down from 14,600 deaths in 1990.
Craniofacial surgery is a surgical subspecialty that deals with congenital and acquired deformities of the head, skull, face, neck, jaws and associated structures. Although craniofacial treatment often involves manipulation of bone, craniofacial surgery is not tissue-specific; craniofacial surgeons deal with bone, skin, nerve, muscle, teeth, and other related anatomy.
Persons with Pierre Robin sequence (PRS) are at greater risk for hearing impairment than persons with cleft lip and/or palate without PRS. One study showed an average of 83% hearing loss in PRS, compared to 60% in cleft individuals without PRS (Handzic et al., 1995). Similarly, PRS individuals typically exhibit conductive, bilateral hearing ...
The Cleft Palate-Craniofacial Journal is a monthly peer-reviewed medical journal. It was established in 1964 as the Cleft Palate Journal , obtaining its current title in 1991. [ 1 ] The journal is published by SAGE Publishing on behalf of the American Cleft Palate-Craniofacial Association .
Nager acrofacial dysostosis, also known as Nager syndrome, is a genetic disorder which displays several or all of the following characteristics: underdevelopment of the cheek and jaw area, down-sloping of the opening of the eyes, lack or absence of the lower eyelashes, kidney or stomach reflux, hammer toes, shortened soft palate, lack of development of the internal and external ear, possible ...
Craniofacial regeneration is necessary following injury to the facial tissue. This can occur during surgery, where doctors fracture the face of a patient in order to correct craniofacial abnormalities such as cleft lip, Apert syndrome, Treacher Collins syndrome, Oligodontia, Cherubism, Crouzon syndrome, Pfeiffer Syndrome, Craniosynostosis, or Goldenhar Syndrome.