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[46] [47] For comparison, 1 mg/day oral estradiol increased SHBG levels by 45%, while 50 μg/day transdermal estradiol increased SHBG levels by 12%. [ 46 ] [ 47 ] Ethinylestradiol is more potent in its effects on liver protein synthesis than either CEEs or estradiol, with 10 μg/day oral ethinylestradiol having been found to be approximately ...
Equine estrogens, or horse estrogens ... Binding affinities were determined via displacement studies in a variety of in-vitro systems with labeled estradiol and ...
The biological half-lives of estrone and estradiol in the circulation are both about 10 to 70 minutes, whereas the biological half-life of estrone sulfate in the circulation is about 10 to 12 hours. [ 5 ] [ 65 ] [ 66 ] The metabolic clearance rate of estrone is 1,050 L/day/m 2 and of estradiol is 580 L/day/m 2 , while that of estrone sulfate is ...
Estradiol has been used at high doses to suppress sex drive in men with sexual deviance such as paraphilias and in sex offenders. [84] [85] [86] It has specifically been used for this indication in the forms of intramuscular injections of estradiol valerate and estradiol undecylate and of subcutaneous pellet implants of estradiol. [84] [85] [86]
Synthetic estradiol, taken orally, decomposes when absorbed in the gastrointestinal tract and delivers bioidentical estradiol to the bloodstream. [23] The hormone estriol, produced during pregnancy, is frequently compounded into bioidentical preparations in the United States.
Equine chorionic gonadotropin (acronym given as eCG but not to be confused with ECG) is a gonadotropic hormone produced in the chorion of pregnant mares. Previously referred to as pregnant mare's serum gonadotropin ( PMSG ), the hormone is commonly used in concert with progestogen to induce ovulation in livestock prior to artificial insemination .
Estradiol cypionate (EC), sold under the brand name Depo-Estradiol among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for trans women, and in hormonal birth control for women. [14] [8] [15] [16] It is given by injection into muscle once every 1 to ...
With intramuscular injections of estradiol valerate, it has been reported that a dose of 5 mg has a duration of 7 to 8 days, 10 mg a duration of 10 to 14 days, 40 mg a duration of 2 to 3 weeks (14 to 21 days), and 100 mg a duration of 3 to 4 weeks (21 to 28 days). [11] [12] [10]