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Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [ 1 ]
Once the compound entered pre-clinical development, process chemistry developed a cost-effective and scalable synthesis. [107] In atorvastatin's case, a key element of the overall synthesis was ensuring stereochemical purity in the final drug substance, and hence establishing the first stereocenter became a key aspect of the overall design.
Continuously varied JPEG compression (between Q=100 and Q=1) for an abdominal CT scan. JPEG (/ ˈ dʒ eɪ p ɛ ɡ / JAY-peg, short for Joint Photographic Experts Group and sometimes retroactively referred to as JPEG 1) [2] [3] is a commonly used method of lossy compression for digital images, particularly for those images produced by digital photography.
JPEG compresses images down to much smaller file sizes, and has become the most widely used image file format. [13] JPEG was largely responsible for the wide proliferation of digital images and digital photos, [14] with several billion JPEG images produced every day as of 2015. [15] Lempel–Ziv–Welch (LZW) is a lossless compression algorithm ...
Medication costs can be the selling price from the manufacturer, that price together with shipping, the wholesale price, the retail price, and the dispensed price. [3]The dispensed price or prescription cost is defined as a cost which the patient has to pay to get medicines or treatments which are written as directions on prescription by a prescribers. [4]
JPEG XR is an image file format that offers several key improvements over JPEG, including: [18] Better compression JPEG XR file format supports higher compression ratios in comparison to JPEG for encoding an image with equivalent quality. Lossless compression JPEG XR also supports lossless compression. The signal processing steps in JPEG XR are ...