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PVP-I is approved for treatment of bacterial vaginosis as a vaginal gel. [18] [19] [20] Brand names include Astodrimer Sodium or Astrodimer 1% Vaginal Gel, Betadine BV, Betafem BV, Viraleze, and VivaGel, among others. [18] [19] [20] Vaginal suppositories are also available and used. [21]
A men's birth control gel has returned promising results in phase 2 trials, but a lack of funding for further testing is a major hurdle.
Vaginal insertion: Every act of intercourse: Spermicidal gel, suppository, or film [38] 21 (1 in 5) 16 (1 in 6.25) Spermicide: Vaginal insertion: Every act of intercourse: 1988 cervical cap and spermicide used by parous (discontinued in 2005) [note 5] Prentif: 32 (1 in 3) 26 (1 in 4) Barrier & spermicide: Vaginal insertion: Every act of intercourse
Results released in February 2009 from a clinical trial of PRO 2000 (Indevus Pharmaceuticals), a vaginal-microbicide gel (0.5%), sparked hope that it might provide modest protection against HIV. [22] The results of a larger trial released in December 2009 showed that PRO 2000 was safe as administered, but was ineffective in reducing the risk of ...
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The ideal vaginal microbicide would have the following characteristics: provide protection against infection not require application at the time of intercourse not harm the natural tissue [3] As of 2009, not harming natural tissue was the most troublesome aspect of development.
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The trial involved 222 men, ages 18 to 50, who applied 5 milliliters of the gel (about a teaspoon) to each of their shoulder blades once per day. The second part of the two-part trial is still ...
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