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H&E stained section of human skin. The dermoepidermal junction or dermal-epidermal junction (DEJ) is the interface between the epidermal and the dermal layers of the skin. The basal cells of the epidermis connect to the basement membrane by the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which ...
The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
Histologic image showing a section of epidermis. Stratum spinosum labeled slightly below center. The stratum spinosum (or spinous layer/prickle cell layer) [1] is a layer of the epidermis found between the stratum granulosum and stratum basale. [2] This layer is composed of polyhedral keratinocytes. [3] [4] These are joined with desmosomes. [3]
Schematic image showing a section of epidermis, with epidermal layers labeled. The epidermis is composed of 4 or 5 layers, depending on the region of skin being considered. [10] Those layers from outermost to innermost are: [2] cornified layer (stratum corneum)
The epidermis is the outermost cell layer of the primary plant body. In some older works the cells of the leaf epidermis have been regarded as specialized parenchyma cells, [1] but the established modern preference has long been to classify the epidermis as dermal tissue, [2] whereas parenchyma is classified as ground tissue. [3]
The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue guarding muscles, bones, ligaments and internal organs. Human skin is similar to most of the other mammals' skin, and it is very similar to pig skin.
A Langerhans cell (LC) is a tissue-resident macrophage of the skin [2] once thought to be a resident dendritic cell. [3] These cells contain organelles called Birbeck granules. They are present in all layers of the epidermis and are most prominent in the stratum spinosum. [4]
Nearly every epithelium rests on a layer of areolar tissue, whose blood vessels provide the epithelium with nutrition, waste removal, and a ready supply of infection-fighting leukocytes when needed. Because of the abundance of open, fluid-filled space, leukocytes can move about freely in areolar tissue and can easily find and destroy pathogens.