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Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
Inflammatory involvement of tertiary syphilis begins at the adventitia of the aortic arch which progressively causes obliterative endarteritis of the vasa vasorum. [3] This leads to narrowing of the lumen of the vasa vasorum, causing ischemic injury of the medial aortic arch and then finally loss of elastic support and dilation of the vessel. [3]
The stages of syphilis are categorized as primary, secondary, latent, and tertiary. It is important to note that neurosyphilis may occur at any stage of infection. [citation needed] Meningitis is the most common neurological presentation in early syphilis. It typically occurs in the secondary stage, arising within one year of initial infection.
Stage 4: Tertiary Stage - Most people with untreated syphilis do not develop tertiary syphilis, but when it does happen, many different organ systems are affected. These include the heart, blood ...
During this phase of the disease, there are no visible signs or symptoms of syphilis. Tertiary stage. It’s not common for people to develop tertiary syphilis, but this stage can be serious. It ...
Syphilis has four stages, each with distinct symptoms, though many people associate it with the wart-like sores that occur during the first stage. Without treatment, syphilis can have long-term ...
The latent stage that results can last a lifetime in many cases. In a few cases, the disease exits latency and enters a tertiary phase, in which destructive lesions of skin, bone, and cartilage ensue. Unlike yaws and bejels, syphilis in its tertiary stage often affects the heart, eyes, and nervous system, as well. [13]
Finally, tertiary syphilis is a very serious condition that happens decades after leaving the infection without treatment. It can damage the organs and even lead to death, according to the CDC. ...
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