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Bacillus thuringiensis (or Bt) is a gram-positive, soil-dwelling bacterium, the most commonly used biological pesticide worldwide. B. thuringiensis also occurs naturally in the gut of caterpillars of various types of moths and butterflies , as well on leaf surfaces, aquatic environments, animal feces, insect-rich environments, flour mills and ...
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Bacillus thuringiensis is a bacterium capable of causing disease of Lepidoptera, Coleoptera and Diptera. The toxin from B. thuringiensis has been incorporated directly into plants via genetic engineering. Bt toxin manufacturers claim it has little effect on other organisms, and is more environmentally friendly than synthetic pesticides.
The activated region of the delta toxin is composed of three distinct structural domains: an N-terminal helical bundle domain (InterPro: IPR005639) involved in membrane insertion and pore formation; a beta-sheet central domain involved in receptor binding; and a C-terminal beta-sandwich domain (InterPro: IPR005638) that interacts with the N-terminal domain to form a channel.
Pesticide application can artificially select for resistant pests. In this diagram, the first generation happens to have an insect with a heightened resistance to a pesticide (red) After pesticide application, its descendants represent a larger proportion of the population, because sensitive pests (white) have been selectively killed.
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