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Immune dysregulation diseases Griscelli syndrome, type II; Innate immune deficiencies NF-Kappa-B Essential Modulator (NEMO) deficiency (Inhibitor of Kappa Light Polypeptide Gene Enhancer in B Cells Gamma Kinase deficiency) Hematologic diseases. Hemoglobinopathies; Sickle cell disease; β thalassemia major (Cooley's anemia) Anemias. Aplastic anemia
The use of embryonic stem cells has also been applied to tendon repair. The embryonic stem cells were shown to have a better survival rate in the tendon as well as better migrating capabilities to reach all areas of damaged tendon. The overall repair quality was also higher, with better tendon architecture and collagen formed.
A stem cell transplant has the potential to cure HIV in part because it requires destroying a person’s cancer-afflicted immune system with chemotherapy and sometimes radiation and replacing it ...
Retroviruses and stem cells were mixed, after which the viruses inserted the gene into the stem cell chromosomes. Stem cells containing the working ADA gene were injected into Andrew's blood. Injections of the ADA enzyme were also given weekly. For four years T cells (white blood cells), produced by stem cells, made ADA enzymes using the ADA ...
A cutting-edge gene therapy has been approved for NHS use for some patients with severe sickle cell disease. Casgevy, also known as exa-cel, was the first treatment to be licensed using gene ...
A woman has undergone a stem-cell therapy made from her own cells, to treat her type 1 diabetes. Researchers in China discovered the woman did not need to use insulin 75 days after the procedure ...
A vast amount research has been conducted in recent years for the use of mesenchymal stem cells to treat multiple sclerosis. [ 17 ] [ 18 ] This form of treatment for the disease has been tested in many studies of experimental allergic encephalomyelitis , the animal model of multiple sclerosis, and several published and on-going phase I and ...
Stem-cell transplantation was pioneered using bone marrow-derived stem cells by a team at the Fred Hutchinson Cancer Research Center from the 1950s through the 1970s led by E. Donnall Thomas, whose work was later recognized with a Nobel Prize in Physiology or Medicine. Thomas' work showed that bone-marrow cells infused intravenously could ...