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Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [ 8 ] [ 9 ] It may also be used for hiccups and muscle spasms near the end of life, [ 9 ] and off-label to treat alcohol use disorder [ 10 ] [ 11 ] or opioid withdrawal symptoms. [ 12 ]
Baclofen [65] or tizanidine are sometimes used as an alternative to benzodiazepines. Tizanidine has been found to have superior tolerability compared to diazepam and baclofen. [66] Benzodiazepines are also used to treat the acute panic caused by hallucinogen intoxication. [67]
Side effects of thiocolchicoside can include nausea, allergy and vasovagal reactions. [15] Liver injury, pancreatitis, seizures, blood cell disorders, severe cutaneous disorders, rhabdomyolysis, and reproductive disorders have all been recorded in the French and European pharmacovigilance databases and in the periodic updates that the companies concerned submit to regulatory agencies.
Baclofen in my view was probably just suppressing alcohol withdrawal symptoms. Baclofen's suppression of temporary withdrawal symptoms may be being misinterpreted as being a successful treatment of alcoholism. We need to be careful about adding primary sources, especially weak primary sources and giving undue weight.
On August 23, 2006, The Wall Street Journal announced that Rite Aid would acquire the U.S. subsidiary of Quebec-based Jean Coutu Group, including 1,858 Eckerd Pharmacy and Brooks Pharmacy stores, for US$3.4 billion in cash and issuing stock, which would also give Jean Coutu a 32% equity stake in Rite Aid.
Cyclobenzaprine 10mg tablets. By mouth, cyclobenzaprine is marketed as Apo-Cyclobenzaprine, Fexmid, Flexeril and Novo-Cycloprine. It is available in generic form. A once-a-day, extended-release formulation, Amrix, is available. [35] Cyclobenzaprine is also used by compounding pharmacies in topical creams. [citation needed]