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The exact cause of lipodermatosclerosis is unknown. [3] [6] Venous disease, such as venous incompetence, venous hypertension, and body mass may be relevant to the underlying pathogenesis. [3] Increased blood pressure in the veins (venous hypertension) can cause diffusion of substances, including fibrin, out of capillaries.
A 2015 Cochrane review of ten studies between 1991 and 2014 suggested a positive effect in reducing tooth decay of xylitol-containing fluoride toothpastes when compared to fluoride-only toothpaste, but there was insufficient evidence to determine whether other xylitol-containing products can prevent tooth decay in infants, children or adults. [25]
Over time, insomnia can also contribute to chronic health issues like heart disease, high blood pressure, obesity, chronic pain syndrome and diabetes. What are the causes or risk factors for insomnia?
Sleep problems in women can manifest at various stages of their life cycle, as supported by both subjective and objective data. [ further explanation needed ] Factors such as hormonal changes, aging, psycho-social aspects, physical and psychological conditions and the presence of sleeping disorders can disrupt women's sleep.
Xylitol is a sugar alcohol, used commonly as a low-calorie sweetener in gums, candies, and oral care products. A study links xylitol to risk of heart attack and stroke.
The safety of sugar substitutes is once again being called into question. Xylitol is associated with an increased risk of heart attack and stroke, according to new Cleveland Clinic research.
Insomnia can be grouped into primary and secondary, or comorbid, insomnia. [124] [125] [126] Primary insomnia is a sleep disorder not attributable to a medical, psychiatric, or environmental cause. [127] There are three main types of primary insomnia.
These movements can lead the patient to wake up, and if so, sleep interruption can be the origin of excessive daytime sleepiness. [2] PLMD is characterized by increased periodic limb movements during sleep, which must coexist with a sleep disturbance or other functional impairment, in an explicit cause-effect relationship.