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Soman (or GD, EA 1210, Zoman, PFMP, A-255, systematic name: O-pinacolyl methylphosphonofluoridate) [1] is an extremely toxic chemical substance. It is a nerve agent , interfering with normal functioning of the mammalian nervous system by inhibiting the enzyme cholinesterase .
OPs are one of the most common causes of poisoning worldwide. [2] There are nearly 3 million poisonings per year resulting in two hundred thousand deaths. [2] [3] Around 15% of people who are poisoned die as a result. [2] Organophosphate poisoning has been reported at least since 1962. [7]
Renal toxicity, animal carcinogenicity. [3] Bezitramide: 2004 Netherlands Risk of fatal overdose [10] Bithionol: 1967 US Dermatologic toxicity. [3] Brotizolam: 1989 UK Animal carcinogenicity. [3] Bromfenac: 1998 US Severe hepatitis and liver failure (requiring transplantation). [2] Bucetin: 1986 Germany Kidney damage [3] Buformin: 1978 Germany ...
This is a partial list of herbs and herbal treatments with known or suspected adverse effects, either alone or in interaction with other herbs or drugs. Non-inclusion of an herb in this list does not imply that it is free of adverse effects.
Beyond their acute toxicity, long-term exposure to organophosphates is associated with a number of heath risks, including organophosphate-induced delayed neuropathy (muscle weakness) and developmental neurotoxicity. [28] [43] [44] There is limited evidence that certain compounds cause cancer, including malathion and diazinon. [45]
More than 10,000 cases of potential calcium channel blocker toxicity occurred in the United States in 2010. [2] When death occurs in medicine overdose, heart medications are the cause more than 10% of time. [2] The three most common types of heart medications that result in this outcome are calcium channel blockers along with beta blockers and ...
Developmental toxicity is any developmental malformation that is caused by the toxicity of a chemical or pathogen. It is the structural or functional alteration, reversible or irreversible, which interferes with homeostasis , normal growth , differentiation , development or behavior.
a major public health problem (thalidomide). However, most studies of reproductive toxicity have focused on occupational or environmental exposure to chemicals and their effects on reproduction. Both consumption of alcohol and tobacco smoking are known to be "toxic for reproduction" in the sense used here.