Search results
Results from the WOW.Com Content Network
Congenital rubella syndrome (CRS) occurs when a human fetus is infected with the rubella virus (German measles) via maternal-fetal transmission and develops birth defects. [1] The most common congenital defects affect the ophthalmologic, cardiac, auditory, and neurologic systems.
Rubella can cause congenital rubella syndrome in the newborn, this being the most severe sequela of rubella. The syndrome (CRS) follows intrauterine infection by the rubella virus and comprises cardiac, cerebral, ophthalmic, and auditory defects. [17] It may also cause prematurity, low birth weight, neonatal thrombocytopenia, anemia, and hepatitis.
Pregnant women with Rubella are at risk of having a miscarriage or having a baby born with multiple birth defects due to Congenital rubella syndrome. It affected around 12.5 million people in the US. An estimated 11,000 pregnancies ended in miscarriage or stillbirth , just over 2,000 newborn babies died , and of those that survived around ...
For premium support please call: 800-290-4726 more ways to reach us
Following a widespread epidemic of rubella infection in 1940, Norman Gregg, an Australian ophthalmologist, reported in 1941 the occurrence of congenital cataracts among 78 infants born following maternal rubella infection in early pregnancy. This indicated that the virus had to cross the placental barrier to reach the fetus and cause malformations.
The genome encodes several non-coding RNA structures; among them is the rubella virus 3' cis-acting element, which contains multiple stem-loops, one of which has been found to be essential for viral replication. [12] The only significant region of homology between rubella and the alphaviruses is located at the NH2 terminus of non structural ...
TORCH syndrome is a cluster of symptoms caused by congenital infection with toxoplasmosis, rubella, cytomegalovirus, herpes simplex, and other organisms including syphilis, parvovirus, and Varicella zoster. [1] Zika virus is considered the most recent member of TORCH infections. [2]
For premium support please call: 800-290-4726 more ways to reach us