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Also sold under the brand names Wellbutrin, Wellbutrin SR and Wellbutrin XL, bupropion hydrochloride (the super science-y name for the prescription drug) dosage can vary based on several factors ...
Comparison of steady-state plasma bupropion levels with bupropion IR 100 mg t.i.d. (3x/day), bupropion SR 150 mg b.i.d. (2x/day), and bupropion XL 300 mg q.d. (1x/day) [3] [109] Bupropion was invented by Nariman Mehta of Burroughs Wellcome (now GlaxoSmithKline ) in 1969, and the US patent for it was granted in 1974. [ 35 ]
Generic bupropion is also used as a medication to help quit smoking. Wellbutrin prevents your brain from reabsorbing the neurotransmitters dopamine and norepinephrine. This can lessen symptoms of ...
Bupropion, on the other hand, is one of the few antidepressants that don’t cause these common side effects, and some research shows it can have the opposite effect — increasing your libido.
In Study 1 (GEMINI), a 6-week randomized controlled trial of dextromethorphan/bupropion versus placebo in people with major depressive disorder, scores on the Montgomery–Åsberg Depression Rating Scale (MADRS)—a scale with a range of 0 to 60 points—decreased with dextromethorphan/bupropion by 15.9 points from a baseline score of 33.6 ...
Abnormal dreams; Aggression; Anaphylactic shock; Angioedema (indicative of a hypersensitivity reaction); Arthralgia; Ataxia; Blood glucose disturbances; Bronchospasm (indicative of a hypersensitivity reaction)
J Clin Psych has online archives only beginning from 1996, so someone has to physically go to the library. The review (see seizure part) and prescribing information give a good enough impression of the seizure liability of bupropion. You can refer to the prescribing information.Paul gene 18:31, 18 August 2007 (UTC) OK, thanks.
Pharmacology of bupropion and its metabolites Bupropion R,R-Hydroxy bupropion S,S-Hydroxy bupropion Threo-hydro bupropion Erythro-hydro bupropion; Exposure and half-life AUC relative to bupropion [8] [9] 1 23.8 0.6 11.2 2.5 Half-life [10] 1.04 h 19 h 15 h 31 h 22 h Inhibition IC 50 (μM) in human cells, unless noted otherwise DAT, uptake [11] 0 ...