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A mole can be either subdermal (under the skin) or a pigmented growth on the skin, formed mostly of a type of cell known as a melanocyte. The high concentration of the body's pigmenting agent, melanin, is responsible for their dark color. Moles are a member of the family of skin lesions known as nevi (singular "nevus"), occurring commonly in ...
Alicia Silverstone had a beauty mark on the left side of her mouth when portraying Batgirl in Batman and Robin. In the Kiff episode "Two Truths and a Bunny", Kennedy the lemur is confident that no one could top her in a game where one player must tell two facts and a fib, and the other participants must spot the fib. But Barry the rabbit, with ...
Others may warrant more thorough examination and biopsy for histopathological examination (looking at a sample of skin under a microscope to detect unique cellular features). For example, a clinician may want to determine whether a pigmented nevus is a type of melanocytic nevus, dysplastic nevus, or melanoma as some of these skin lesions pose a ...
Causes of melanoma. Ultraviolet light exposure from the sun or from tanning beds causes most melanomas. Melanoma may appear at a spot where you have an existing mole. But if an unusual spot shows ...
The adaptation of lighter skin is needed so that individuals in higher latitudes can still absorb enough UV for the production of vitamin D. [9] Freckled individuals tend to tan less and have very light skin, an adaptation to allow individuals that expressed these genes to synthesise sufficient vitamin D. Freckles on a female face after summertime
Congenital nevus. Note the variable coloration and slightly irregular border. The congenital melanocytic nevus appears as a circumscribed, light brown to black patch or plaque, potentially very heterogeneous in consistency, covering any size surface area and any part of the body.
It is normally found in the elderly (peak incidence in the 9th decade), on skin areas with high levels of sun exposure like the face and forearms. Incidence of evolution to lentigo maligna melanoma is low, about 2.2% to 5% in elderly patients. It is also known as "Hutchinson's melanotic freckle". [3] This is named for Jonathan Hutchinson.
Various differential diagnoses of pigmented skin lesions, including dysplastic nevus, showing the relative incidence of biopsied lesions, and malignancy potential. When an atypical mole has been identified, a skin biopsy takes place in order to best diagnose it. Local anesthetic is used to numb the area, then the mole is biopsied.