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Phenylephrine is a selective α 1 -adrenergic receptor agonist with minimal to no β-adrenergic receptor agonist activity or induction of norepinephrine release. [5][8][15] It causes constriction of both arteries and veins. [12] Phenylephrine was patented in 1933 [16] and came into medical use in 1938. [17]
This is a list of abbreviations used in medical prescriptions, including hospital orders (the patient-directed part of which is referred to as sig codes). This list does not include abbreviations for pharmaceuticals or drug name suffixes such as CD, CR, ER, XT (See Time release technology § List of abbreviations for those).
In clinical trials, the most common adverse events which occurred at a rate ≥5% and ≥1.5 times placebo included paraesthesia (tingling in fingers/toes), dizziness, altered taste, insomnia, constipation, and dry mouth.
Phentermine (phenyl-tertiary-butyl amine), sold under the brand name Ionamin among others, is a medication used together with diet and exercise to treat obesity. [3] It is taken by mouth for up to a few weeks at a time, after which the benefits subside. [3]
Substituted amphetamines are a class of compounds based upon the amphetamine structure; [1] it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents. [1][2][3][4] The compounds in this class span a variety of pharmacological subclasses ...
Fenfluramine as a single drug was first introduced in the 1970s, but was not popular because it only temporarily reduced weight. [1] A 1984 study found a weight loss of 7.5 kg on average in 24 weeks, as compared to 4.4 kg under placebo. [4] It sold modestly until the 1990s, when it was combined with phentermine and heavily marketed.
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J. Robert Oppenheimer. J. Robert Oppenheimer (born Julius Robert Oppenheimer; / ˈɒpənhaɪmər / OP-ən-hy-mər; April 22, 1904 – February 18, 1967) was an American theoretical physicist who served as the director of the Manhattan Project 's Los Alamos Laboratory during World War II. He is often called the "father of the atomic bomb " for ...
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