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Paroxetine, sold under the brand name Paxil among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7] It is used to treat major depressive disorder , obsessive-compulsive disorder , panic disorder , social anxiety disorder , post-traumatic stress disorder , generalized anxiety disorder , and premenstrual ...
Occasionally symptoms can last up to one year. [3] They typically resolve within a day of restoring the medication. [ 20 ] Paroxetine and venlafaxine seem to be particularly difficult to discontinue, and prolonged withdrawal syndrome (post-acute-withdrawal syndrome, or PAWS) lasting over 18 months has been reported with paroxetine.
Paroxetine, sold under the name Paxil, isn’t prescribed as often as fluoxetine, sertraline or escitalopram. But it’s still one of the most widely prescribed antidepressants in the country.
In general, large-scale studies do tend to show that long-term use of antidepressants is associated with weight gain side effects. However, study data on escitalopram and weight changes is very ...
[175] [176] Discontinuation effects appear to be less for fluoxetine, perhaps owing to its long half-life and the natural tapering effect associated with its slow clearance from the body. One strategy for minimizing SSRI discontinuation symptoms is to switch the patient to fluoxetine and then taper and discontinue the fluoxetine.
Online, people claim they get brain zaps after stopping use of drugs like Lexapro (escitalopram), Cymbalta (duloxetine), and Paxil (paroxetine), but they can happen when you stop taking any type ...
Fluoxetine also has a long half-life which can reduce withdrawal symptoms which are characteristic for some SSRIs after abrupt discontinuation, but it also means that it takes a long time to clear the drug and its active metabolite after discontinuing fluoxetine treatment. [18] Figure 5 Chemical structure of (–)-(3S,4R)-paroxetine
Last but certainly not least, some tricyclic antidepressants (TCAs) are used to treat anxiety disorders. Tricyclics are also an older class of antidepressants first developed in the 1950s.