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The post Why I Started and Stopped Taking the “Anti-Aging” Drug Rapamycin appeared first on AGEIST. I am a healthy sixty-one-year-old man. Addressing my health, fitness, and longevity has been ...
mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...
Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).
Tacrolimus was discovered in 1987; it was among the first macrolide immunosuppressants discovered, preceded by the discovery of rapamycin (sirolimus) on Rapa Nui (Easter Island) in 1975. [44] It is produced by a soil bacterium, Streptomyces tsukubensis. [45] The name tacrolimus is derived from "Tsukuba macrolide immunosuppressant". [46]
A new study suggests that the drug rapamycin may delay ovarian aging, extending fertility and delaying the onset of menopause by as much as five years. Common drug could extend women's fertility ...
More: Why you should reconsider taking daily aspirin. What is the new recommendation for aspirin? The latest medical recommendations for aspirin require a bit more nuance, health experts say.
Besides rapamycin and senolytics, the drug-repurposing candidates studied most extensively include metformin, acarbose, spermidine and NAD+ enhancers. [110] Many prolongevity drugs are synthetic alternatives or potential complements to existing nutraceuticals, such as various sirtuin-activating compounds under investigation like SRT2104. [111]
Here are seven supplement combinations you should not take together or should be careful about combining. Related: 7 Things You Should Look for When Buying a Supplement, According to Dietitians 1.
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