Search results
Results from the WOW.Com Content Network
Guanidinium chloride is a weak acid with a pK a of 13.6. The reason that it is such a weak acid is the complete delocalisation of the positive charge through 3 nitrogen atoms (plus a little bit positive charge on carbon). However, some stronger bases can deprotonate it, such as sodium hydroxide:
Guanidine exists protonated, as guanidinium, in solution at physiological pH. Guanidinium chloride (also known as guanidine hydrochloride) has chaotropic properties and is used to denature proteins. Guanidinium chloride is known to denature proteins with a linear relationship between concentration and free energy of unfolding.
Guanidinium chloride; Guanidinium thiocyanate This page was last edited on 23 October 2021, at 14:51 (UTC). Text is available under the Creative Commons ...
Guanidinium chloride; Guanidinium thiocyanate; S. Sodium iodide This page was last edited on 26 February 2020, at 06:51 (UTC). Text is available under the ...
Guanidinium thiocyanate can be used to deactivate a virus, such as the influenza virus that caused the 1918 "Spanish flu", so that it can be studied safely.. Guanidinium thiocyanate is also used to lyse cells and virus particles in RNA and DNA extractions, where its function, in addition to its lysing action, is to prevent activity of RNase enzymes and DNase enzymes by denaturing them.
This is a list of CAS numbers by chemical formulas and chemical compounds, indexed by formula.The CAS number is a unique number applied to a specific chemical by the Chemical Abstracts Service (CAS).This list complements alternative listings to be found at list of inorganic compounds and glossary of chemical formulae
A further explanation of how DNA binds to silica is based on the action of guanidinium chloride (GuHCl), which acts as a chaotrope. [3] A chaotrope denatures biomolecules by disrupting the shell of hydration around them.
CAS Number. 3483-12-3 ... or in the presence of a strong denaturant such as 6 M guanidinium chloride, 8 M urea, or 1% sodium dodecylsulfate).