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Sheila eventually overcomes her agoraphobia and continues to spend a great deal of her time with Frank. Toward the end of Season 2, Sheila meets Frank's mother Peggy, and the two initially despise each other. Peggy is then diagnosed with terminal cancer, and moves into Sheila's home after starting a fire in the Gallagher's basement from a meth lab.
As Sheila overcomes more of her agoraphobia, a concerned Frank finds a new financial plan in former bar patron Dottie, whose declining health makes her an ideal match for him. Dottie bonds with Frank but rejects his sexual advances, revealing that her heart could explode if her blood pressure rises.
Fiona makes it clear the family does not like Monica, and states that if Monica truly loves her children, she will leave Liam with his siblings. Angered over Eddie's actions, Sheila furiously follows Eddie out of the house, overcoming her agoraphobia in the process. Frank notes that she has left her house, and she enthusiastically celebrates.
Sheila furiously kicks Eddie out of her house, overcoming her agoraphobia in the process. Eddie's betrayal and lack of affection spirals Karen into a mental breakdown; wanting to get revenge on her father, Karen rapes an incapacitated Frank, showcasing the incident on a video blog that she sends to Eddie and his co-workers.
Sheila uses ropes to tie herself to the house to retrieve Liam, briefly overcoming her agoraphobia. Seeing that Kash ( Pej Vahdat ) was punched in the eye by Mickey ( Noel Fisher ), Ian decides to confront Mickey at his house.
Meanwhile, Sheila (Joan Cusack) gets a VR headset, in hopes that it could cure her agoraphobia, but experiences a mental breakdown when her nurse tries to deviate from the instructions. Without Frank on board, Fiona is forced to attend a meeting with Carl's principal, who explain Carl's actions have raised concerns among the committee.
Per Debbie's advice, Sheila tries to reconcile with Karen, apologizing for being absent during Karen's childhood due to her agoraphobia. Karen is tearful over the apology, but before she can respond, she receives a text from Lip to meet him at the park.
Joshua Alston of The A.V. Club gave the episode a "B" grade and wrote, ""A Good Cause" was a battle between the version of Shameless I like — the one that is poignant and rings true even when its class shadings are foreign to me — and the version that completely drains me, the one that seems to exist only as an exercise in boundary-pushing ...