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The Punnett square is a tabular summary of possible combinations of maternal alleles with paternal alleles. [9] These tables can be used to examine the genotypical outcome probabilities of the offspring of a single trait (allele), or when crossing multiple traits from the parents.
One of the common diagrams used to predict the result of cross-breeding is the Punnett square. [49] When studying human genetic diseases, geneticists often use pedigree charts to represent the inheritance of traits. [50] These charts map the inheritance of a trait in a family tree.
Maurice Karnaugh introduced the technique in 1953 [1] [2] as a refinement of Edward W. Veitch's 1952 Veitch chart, [3] [4] which itself was a rediscovery of Allan Marquand's 1881 logical diagram [5] [6] or Marquand diagram. [4]
The first uses of test crosses were in Gregor Mendel’s experiments in plant hybridization.While studying the inheritance of dominant and recessive traits in pea plants, he explains that the “signification” (now termed zygosity) of an individual for a dominant trait is determined by the expression patterns of the following generation.
This is a Punnett square for Rh factor inheritance. This square specifically shows two heterozygous Rh positive parents and the possible genotypes/phenotypes the offspring could have. The D antigen is inherited as one gene (on the short arm of the first chromosome, p36.13–p34.3) with various alleles. Typically, Rhesus positive people have an ...
Punnett squares for each combination of parents' color vision status giving probabilities of their offsprings' status; A superscript 'c' denotes a chromosome with an affected gene. By far the most common form of color blindness is congenital red–green color blindness (Daltonism), which includes protanopia/protanomaly and deuteranopia ...
Punnett square of the possible genotypes and phenotypes of children given the genotypes and phenotypes of their mothers (rows) and fathers (columns) shaded by phenotypes (A: amber, B: blue, AB: green and O: grey) by CMG Lee. Source: Own work: Author: Cmglee
Punnett square for three-allele case (left) and four-allele case (right). White areas are homozygotes. Colored areas are heterozygotes. Consider an extra allele frequency, r. The two-allele case is the binomial expansion of (p + q) 2, and thus the three-allele case is the trinomial expansion of (p + q + r) 2.
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