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Magnesium sulfate is effective in decreasing the risk that pre-eclampsia progresses to eclampsia. [24] Intravenous magnesium sulfate is used to prevent and treat seizures of eclampsia. It reduces the systolic blood pressure but does not alter the diastolic blood pressure, so the blood perfusion to the fetus is not compromised.
Magnesium sulfate may be used to prevent eclampsia in those with severe disease. [4] Bed rest and salt intake have not been found to be useful for either treatment or prevention. [3] [4] Pre-eclampsia affects 2–8% of pregnancies worldwide.
The use of intravenous or intramuscular magnesium sulfate improves outcomes in those with severe pre-eclampsia and eclampsia and is generally safe. [ 4 ] [ 13 ] Treatment options include blood pressure medications such as hydralazine and emergency delivery of the baby either vaginally or by cesarean section .
As a bronchodilator after beta-agonist and anticholinergic agents have been tried, e.g. in severe exacerbations of asthma. [4]Obstetrics: Magnesium sulfate is used to prevent seizures in women with preeclampsia and eclampsia, and is also used for fetal neuroprotection in preterm deliveries, but has been shown to be an ineffective tocolytic agent.
Magnesium sulfate or magnesium sulphate is a chemical compound, a salt with the formula MgSO 4, consisting of magnesium cations Mg 2+ (20.19% by mass) and sulfate anions SO 2− 4. It is a white crystalline solid , soluble in water but not in ethanol .
Commonly used tocolytic medications include β 2 agonists, calcium channel blockers, NSAIDs, and magnesium sulfate. These can assist in delaying preterm delivery by suppressing uterine muscle contractions and their use is intended to reduce fetal morbidity and mortality associated with preterm birth. [2]
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1540 Olentangy River Rd, Columbus, OH · Directions · (614) 299-2253