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Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, along with numerous other biological functions. [ 1 ] [ 2 ] In humans, the most significant compounds within this group are vitamin D 3 ( cholecalciferol ) and vitamin D 2 ( ergocalciferol ).
Ergocalciferol, also known as vitamin D 2 and nonspecifically calciferol, is a type of vitamin D found in food. It is used as a dietary supplement [ 3 ] to prevent and treat vitamin D deficiency [ 4 ] due to poor absorption by the intestines or liver disease . [ 5 ]
Calcitriol was identified as the active form of vitamin D in 1971 and the drug was approved for medical use in the United States in 1978. [7] It is available as a generic medication . [ 12 ] In 2022, it was the 254th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
Vitamin D is a unique nutrient in that it comes from the food we eat and is a hormone that our bodies make. The fat-soluble vitamin has a slew of important functions and health benefits, from ...
The pharmacological definition cannot apply to these substances because utilization and absorption is a function of the nutritional status and physiological state of the subject, [10] resulting in even greater differences from individual to individual (inter-individual variation). Therefore, bioavailability for dietary supplements can be ...
The U.S. Preventive Services Task Force released a draft recommendation advising against using vitamin D to prevent falls and fractures in people over 60. Pharmacist Katy Dubinsky weighs in.
There's no magic hour for taking this key player in vision health, but taking it with food may be smart since it's a fat-soluble vitamin. Vitamin E is also essential for good blood, skin and brain ...
Since vitamin D 3 (cholecalciferol) and vitamin D 2 (ergocalciferol) are fat-soluble, humans and other animals with a skeleton need to store some fat. Without fat, the animal will have a hard time absorbing vitamin D 2 and vitamin D 3 , and the lower the fat percentage, the greater the risk of vitamin deficiency, which is the case in some ...