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  2. Glucocorticoid remediable aldosteronism - Wikipedia

    en.wikipedia.org/wiki/Glucocorticoid_remediable...

    The last part is either mediated by the aldosterone synthase (for aldosterone) or by the 11β-hydroxylase (for corticosterone). [citation needed] Aldosterone synthesis is stimulated by several factors: [citation needed] by increase in the plasma concentration of angiotensin III. by increased plasma angiotensin II, ACTH, or potassium levels.

  3. Aldosterone-to-renin ratio - Wikipedia

    en.wikipedia.org/wiki/Aldosterone-to-renin_ratio

    The cutoff normal individuals from those with primary hyperaldosteronism is significantly affected by the conditions of testing, such as posture and time of day. On average, an ARR cutoff of 23.6 ng/dL per ng/(mL·h), expressed in alternative units as 651 pmol/L per μg/(L·h), has been estimated to have a sensitivity of 97% and specificity of 94%. [2]

  4. Aldosterone - Wikipedia

    en.wikipedia.org/wiki/Aldosterone

    Hyperaldosteronism is abnormally increased levels of aldosterone, while hypoaldosteronism is abnormally decreased levels of aldosterone. A measurement of aldosterone in blood may be termed a plasma aldosterone concentration (PAC), which may be compared to plasma renin activity (PRA) as an aldosterone-to-renin ratio.

  5. Hypoaldosteronism - Wikipedia

    en.wikipedia.org/wiki/Hypoaldosteronism

    Potassium levels, plasma aldosterone concentration and plasma renin activity are the three most useful in the first instance. Low aldosterone levels in the presence of high renin activity, often with low sodium, high potassium, is associated with primary hypoaldosteronism.

  6. Primary aldosteronism - Wikipedia

    en.wikipedia.org/wiki/Primary_aldosteronism

    For people with hyperplasia of both glands, successful treatment is often achieved with spironolactone or eplerenone, drugs that block the aldosterone receptor. With its antiandrogen effect, spironolactone drug therapy may have a range of side effects in males and females, including gynecomastia and irregular menses. These symptoms occur less ...

  7. Hyperaldosteronism - Wikipedia

    en.wikipedia.org/wiki/Hyperaldosteronism

    Hyperaldosteronism is a medical condition wherein too much aldosterone is produced. High aldosterone levels can lead to lowered levels of potassium in the blood (hypokalemia) and increased hydrogen ion excretion . Aldosterone is normally produced in the adrenal glands.

  8. Pseudohyperaldosteronism - Wikipedia

    en.wikipedia.org/wiki/Pseudohyperaldosteronism

    Pseudohyperaldosteronism (also pseudoaldosteronism) is a medical condition which mimics the effects of elevated aldosterone (hyperaldosteronism) by presenting with high blood pressure, low blood potassium levels (hypokalemia), metabolic alkalosis, and low levels of plasma renin activity (PRA).

  9. Feline hyperaldosteronism - Wikipedia

    en.wikipedia.org/wiki/Feline_Hyperaldosteronism

    Primary hyperaldosteronism (PHA) is a disorder of the adrenal cortex that causes increased circulating aldosterone levels. There are two types of PHA. One type is caused by a unilateral aldosterone-producing adenoma or adenocarcinoma. The other type, known as idiopathic hyperaldosteronism, occurs with bilateral adrenal hyperplasia. [1]