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Autoimmune inner ear disease (AIED) was first defined by Dr. Brian McCabe in a landmark paper describing an autoimmune loss of hearing. [2] The disease results in progressive sensorineural hearing loss (SNHL) that acts bilaterally and asymmetrically, and sometimes affects an individual's vestibular system .
Susac's syndrome (retinocochleocerebral vasculopathy) is a very rare form of microangiopathy characterized by encephalopathy, branch retinal artery occlusions and hearing loss. [1] The cause is unknown but it is theorized that antibodies are produced against endothelial cells in tiny arteries which leads to damage and the symptoms related to ...
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
Hearing loss completely recovers in around 35–39% of patients with SSNHL, usually within one to two weeks from onset. [34] Steroid treatment within seven days, a lower initial severity of hearing loss, the absence of vertigo, younger patient age, and a history of cardiovascular disease are all associated with complete hearing recovery. [35]
The technology can uniquely identify a person by analyzing the antibodies in body fluids. A unique, individual set of antibodies, called individual specific autoantibodies (ISA), is found in blood, serum, saliva, urine, semen, perspiration, tears, and body tissues, and the antibodies are not affected by illness, medication, or food/drug intake.
Anti-NMDA receptor encephalitis is a type of brain inflammation caused by antibodies. [4] Early symptoms may include fever, headache, and feeling tired. [1] [2] This is then typically followed by psychosis which presents with false beliefs (delusions) and seeing or hearing things that others do not see or hear (hallucinations). [1]
Ashton Kutcher said he lost his ability to walk and see for nearly a year after being diagnosed with vasculitis. Vasculitis is an autoimmune disorder caused by inflammation to blood vessels.
Two investigations have provided evidence that anti-RNP antibodies have a role in the development of MCTD by linking antibody emergence to clinical illness. [ 63 ] [ 64 ] Beyond antibody formation, B cells can serve in a variety of other important immunological pathways, including as antigen presentation, pathogenic cytokine secretion, and ...