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Moxidectin was approved for onchocerciasis (river-blindness) in 2018 for people over the age of 11 in the United States based on two studies. [5] There is a need for additional trials, with long-term follow-up, to assess whether moxidectin is safe and effective for treatment of nematode infection in children and women of childbearing potential. [6]
Thelazia is a genus of nematode worms which parasitize the eyes and associated tissues of various bird and mammal hosts, including humans. [2] [3] They are often called "eyeworms", and infestation with Thelazia species is referred to as "thelaziasis" (occasionally spelled "thelaziosis").
Ivermectin is an antiparasitic drug. [7] After its discovery in 1975, [8] its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. [9] Approved for human use in 1987, [10] it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis.
Eye symptoms provide the common name associated with onchocerciasis, river blindness, and may involve any part of the eye from conjunctiva and cornea to uvea and posterior segment, including the retina and optic nerve. [20] [21] The microfilariae migrate to the surface of the cornea. Punctate keratitis occurs in the infected area. This clears ...
It should not be used for worm infections of the eye. [4] It is taken by mouth. [3] Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. [4] While it may be used during pregnancy, it is not recommended for use during breastfeeding. [4] Praziquantel is in the anthelmintic class of ...
For the treatment of human cases, removal of the worm is suggested. Topical treatment with cocaine or thiabendazole have also been reported to kill the worms in human cases. [ 8 ] Because most, if not all, species of Thelazia are spread by flies, sanitary practices which reduce the presence of flies will also reduce the spread of thelaziasis.
Oxfendazole is an anthelmintic (wormer) compound used in veterinary practice. It comes under the chemical class of the benzimidazoles. This drug is barely used in horses, [3] goats, sheep, and cattle. It is very scarcely applied on dogs and cats.
Levamisole, sold under the brand name Ergamisol among others, is a medication used to treat parasitic worm infections, specifically ascariasis and hookworm infections. [1] It is taken by mouth. [2] Side effects may include abdominal pain, vomiting, headache, and dizziness. [2] Use is not recommended during breastfeeding or the third trimester ...
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