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Horizontal gene transfer is the primary mechanism for the spread of antibiotic resistance in bacteria, [8] [5] [9] [10] and plays an important role in the evolution of bacteria that can degrade novel compounds such as human-created pesticides [11] and in the evolution, maintenance, and transmission of virulence. [12]
This lateral gene transfer occurred also beyond the Darwinian threshold, after heredity or vertical gene transfer was established. [4] [5] "Sequence comparisons suggest recent horizontal transfer of many genes among diverse species including across the boundaries of phylogenetic "domains". Thus determining the phylogenetic history of a species ...
Horizontal gene transfer was first observed in 1928, in Frederick Griffith's experiment: showing that virulence was able to pass from virulent to non-virulent strains of Streptococcus pneumoniae, Griffith demonstrated that genetic information can be horizontally transferred between bacteria via a mechanism known as transformation. [2]
An example is the viral transfer of DNA from one bacterium to another and hence an example of horizontal gene transfer. [2] [3] [page needed] Transduction does not require physical contact between the cell donating the DNA and the cell receiving the DNA (which occurs in conjugation), and it is DNase resistant (transformation is susceptible to ...
A large body of molecular evidence supports a variety of mechanisms for large evolutionary changes, including: genome and gene duplication, which facilitates rapid evolution by providing substantial quantities of genetic material under weak or no selective constraints; horizontal gene transfer, the process of transferring genetic material to ...
In this image, a gene from one bacterial cell is moved to another bacterial cell. This process of the second bacterial cell taking up new genetic material is called transformation. In molecular biology and genetics , transformation is the genetic alteration of a cell resulting from the direct uptake and incorporation of exogenous genetic ...
Horizontal transmission is the transmission of organisms between biotic and/or abiotic members of an ecosystem that are not in a parent-progeny relationship. Because the evolutionary fate of the agent is not tied to reproductive success of the host, horizontal transmission tends to evolve virulence .
Horizontal gene transfer is the primary mechanism for the spread of antibiotic resistance in bacteria. Although homologous recombination varies widely among different organisms and cell types, for double-stranded DNA ( dsDNA ) most forms involve the same basic steps.