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Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
Guaifenesin/codeine is a fixed-dose combination cold medicine used for the treatment of cough. [1] It contains guaifenesin, an expectorant; and codeine, as the phosphate, an opioid antitussive. [1] It is taken by mouth. [1] It was approved for medical use in the United States in 2006. [1]
This mechanism is most likely responsible for the mucolytic effects of the drug, but may also explain the reported activity in Gaucher and Parkinson's disease. Both ambroxol and its parent drug bromhexine have been shown to induce autophagy in several cell types, and ambroxol was shown to potentiate rifampicin therapy in a model of tuberculosis ...
For instant relief from a chest-wracking cough, suck on a cough drop or lozenge. The most common ingredient in cough drops is menthol , which is naturally found in the mint plant and provides a ...
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Guaifenesin is an oral medication used to try to help cough out phlegm from the airways. [1] It is often used in combination with other medications. [1] It is believed to work by making airway secretions more liquid. [1] Side effects may include dizziness, sleepiness, skin rash, and nausea. [2] Guaifenesin has been used medically since at least ...
It is commonly available in cough syrups and also as sustained-release tablets. Mucolytics can dissolve thick mucus and are usually used to help relieve respiratory difficulties. They do this by breaking down the chemical bonds between molecules in the mucus. [5] This in turn can lower the viscosity by altering the mucin-containing components.
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