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Microscopically, the organization of liver parenchyma can be represented by three different schematics: (1) the classic (hepatic) lobule, (2) the portal lobule, and (3) the hepatic acinus. Classic (hepatic) lobules are based upon blood flow.
Anatomically the liver consists of four lobes: two larger ones (right and left) and two smaller ones (quadrate and caudate). Histologically speaking, it has a complex microscopic structure, that can be viewed from several different angles.
Liver – Normal Histology Click on the Annotations box below each unlabelled picture to reveal the annotated versions. Annotations Expand Annotations Expand Annotations Expand Back to Normal Histology Hepatobiliary System and Pancreas Pathology
Histology of the liver - lobules, central veins, hepatocytes, portal triads (hepatic arteries, portal venules, bile ductules), and bile ducts.
Acute hepatitic patterns involve the parenchyma more than the portal areas, with hepatocyte apoptosis and numerous foci of lymphocytes and macrophages disrupting the normal sinusoidal architecture of the liver, a finding termed lobular disarray.
Recall normal liver anatomy and histology. 2. Understand basic terminology/definitions. 3. Understand the general patterns of injury, repair and fibrosis. 4. Exposure to common liver tumors. cells thick). Sinusoidal spaces lined by endothelial cells and filled with blood, Kupffer cells and stellate cells. Others...
Normal Liver Histology The liver parenchyma is composed of small lobules of a roughly hexagonal shape with portal tracts at the apices. Inside the lobules, the hepatocytes are arranged as cords of cells connecting the portal tracts in the periphery to the central veins (terminal branch of hepatic veins).