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Phenylalanine ball and stick model spinning. Phenylalanine (symbol Phe or F) [3] is an essential α-amino acid with the formula C 9 H 11 NO 2.It can be viewed as a benzyl group substituted for the methyl group of alanine, or a phenyl group in place of a terminal hydrogen of alanine.
Standard phenylalanine concentrations in unaffected persons are about 2-6mg/dl (120–360 μmol/L) phenylalanine concentrations in those with untreated hyperphenylalaninemia can be up to 20 mg/dL (1200 μmol/L). Measurable IQ deficits are often detected as phenylalanine levels approach 10 mg/dL (600 mol/L).
2-Amino-3-phenyl-propanoic acid Abbreviations: F, Phe Synonyms: alpha-Amino-beta-phenylpropionic acid ... (phenylalanine) ^a CID 71567 from PubChem (D-phenylalanine)
Asparagine→Aspartic acid (ASN126ASP) G6PD-Mediterranean Gd-Med G6PD B +305900.0006 Substitution nucleotide C→T: 563 (Exon 6) 188 Serine→Phenylalanine (SER188PHE) Class II G6PD-Canton Gd-Canton G6PD B +305900.0021 Substitution nucleotide G→T: 1376 459 Arginine→Leucine (ARG459LEU) Class II G6PD-Chatham Gd-Chatham G6PD +305900.0003
Placeholder when the amino acid is unknown or unimportant. Tyrosine: Y Tyr Tyr behaves similarly to phenylalanine (precursor to tyrosine) and tryptophan, and is a precursor of melanin, epinephrine, and thyroid hormones. Naturally fluorescent, its fluorescence is usually quenched by energy transfer to tryptophans. Glutamic acid or glutamine: Z Glx
This is especially true for Healthy life expectancy, the definition of which criteria may change over time, even within a country. For example, Canada is a country with a fairly high overall life expectancy at 81.63 years; however, this number decreases to 75.5 years for Indigenous people in the country. [4]
The average life expectancy of all domestic cat breeds was 11.7 years. Crossbreeds and Siamese came very close to that mark at 11.9 and 11.7 years, respectively.
Phenylalanine is a large, neutral amino acid (LNAA). LNAAs compete for transport across the blood–brain barrier (BBB) via the large neutral amino acid transporter (LNAAT). If phenylalanine is in excess in the blood, it will saturate the transporter. Excessive phenylalanine levels tend to decrease the levels of other LNAAs in the brain.