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A review for Boston Magazine called Sinclair "one of science's most controversial figures" and said many in the scientific community were skeptical of claims he made about human longevity. University of Alabama biology professor Steven N. Austad said, "David is a good friend, but I do think he's been guilty of making excessive claims."
David Andrew Sinclair AO (born June 26, 1969) is an Australian-American biologist and academic known for his research on aging and epigenetics. Sinclair is a professor of genetics at Harvard Medical School and the founding director of the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging at Harvard.
OvaScience was a publicly traded biotechnology company, focused on female infertility.It was founded in 2011 by Michelle Dipp, Richard Aldrich, Christoph Westphal, Jonathan Tilly, and David Sinclair and is based on scientific work done by Tilly concerning mammalian oogonial stem cells and work on mitochondria by Sinclair.
Taking vitamin D supplements did not result in a “significantly lower risk” of fractures among middle-age and older adults in one study published in 2022 in the New England Journal of Medicine.
[53] [58] [59] [60] In 2004, Harvard University professor David Sinclair co-founded Sirtris Pharmaceuticals, the initial product of which was a resveratrol formulation. [ 61 ] [ 62 ] [ 63 ] Sirtris was purchased and made a subsidiary of GlaxoSmithKline in 2008 for $720 million and shut down in 2013, without successful drug development.
David Sinclair and Rachel Drake shattered records in winning the men's and women's titles in the 62nd annual JFK 50 Mile ultramarathon on Saturday. Sinclair, 32, of South Burlington, Vermont, took ...
STACs have been discovered by Konrad Howitz of Biomol Inc and biologist David Sinclair. In September 2003, Howitz and Sinclair et al. published a highly cited paper reporting that polyphenols such as resveratrol [ 2 ] activate human SIRT1 and extend the lifespan of budding yeast (Howitz et al., Nature, 2003).
A 2009 review of longevity research noted: "Extrapolation from worms to mammals is risky at best, and it cannot be assumed that interventions will result in comparable life extension factors. Longevity gains from dietary restriction, or from mutations studied previously, yield smaller benefits to Drosophila than to nematodes, and smaller still ...
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