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Cefixime, sold under the brand name Suprax among others, is an antibiotic medication used to treat a number of bacterial infections. [5] These infections include otitis media , strep throat , pneumonia , urinary tract infections , gonorrhea , and Lyme disease . [ 5 ]
One of the most prevalent forms of adverse drug reactions is cutaneous reactions, [1] with drug-induced urticaria ranking as the second most common type, preceded by drug-induced exanthems. [2] Urticaria, commonly known as hives , manifests as weals, itching, burning, redness, swelling, and angioedema —a rapid swelling of lower skin layers ...
This page was last edited on 19 January 2024, at 04:21 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Hives, also known as urticaria, is a kind of skin rash with red and/or flesh-colored, raised, itchy bumps. [1] Hives may burn or sting. [ 2 ] The patches of rash may appear on different body parts, [ 2 ] with variable duration from minutes to days, and do not leave any long-lasting skin change. [ 2 ]
Urticarial (hives), anaphylaxis, angioedema. TypeII Antibody-mediated IgM, IgG antibody binds antigen leading to complement-driven cell lysis drug-induced thrombocytopenia, hemolytic anemia, Goodpasture's, ANCA vasculitis. Type III Immune complex IgM, IgG, IgA antigen-antibody complex deposits in tissues-triggers recruitment of leukocytes
Chronic spontaneous urticaria, despite its cause being unknown, is linked to a higher prevalence of autoimmune diseases, and is often worsened by triggers like stress, infections, certain foods, or nonsteroidal anti-inflammatory drugs. The hives and angioedema seen in CSU is thought to be linked to the degranulation of skin mast cells.
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β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
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