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Docosapentaenoic acid (DPA) is an n-3 fatty acid that is structurally similar to eicosapentaenoic acid (EPA) with the same number of double bonds, but two more carbon chain units. [4] Dietary sources. These are the top five sources for DPA according to the USDA Agricultural Research Service: [5] Fish oil, menhaden 0.668 g in 1 tbsp. (13.6 g)
[2] Mammals are unable to synthesize omega−3 fatty acids, but can obtain the shorter-chain omega−3 fatty acid ALA (18 carbons and 3 double bonds) through diet and use it to form the more important long-chain omega−3 fatty acids, EPA (20 carbons and 5 double bonds) and then from EPA, the most crucial, DHA (22 carbons and 6 double bonds). [2]
The FDA recommends that consumers do not exceed more than 3 grams per day of EPA and DHA combined, with no more than 2 grams from a dietary supplement. [90] This is not the same as 3000 mg of fish oil. A 1000 mg pill typically has only 300 mg of omega−3; 10 such pills would equal 3000 mg of omega−3.
Intake of large doses (2.0 to 4.0 g/day) of long-chain omega−3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses the effects can be significant (from 20% to 35% and even up to 45% in individuals with levels greater than 500 mg/dL).
Menhaden is a blend of poghaden (pogy for short) and an Algonquian word akin to Narragansett munnawhatteaûg, derived from munnohquohteau ("he fertilizes"), referring to their use of the fish as fertilizer. [2] It is generally thought that Pilgrims were advised by Tisquantum (also known as Squanto) to plant menhaden with their crops. [2]
[2] [7] Intake of large doses (2.0 to 4.0 g/day) of long-chain omega−3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses, the effects can be significant (from 20% to 35% and even up to 45% in individuals with levels greater than 500 mg/dL).
Fat has a food energy content of 38 kilojoules per gram (9 kilocalories per gram) proteins and carbohydrates 17 kJ/g (4 kcal/g). [ 2 ] Water makes up a large proportion of the total mass ingested as part of a normal diet but it does not provide any nutritional value.
In biochemistry, docosanoids are signaling molecules made by the metabolism of twenty-two-carbon fatty acids (EFAs), especially the omega-3 fatty acid, docosahexaenoic acid (DHA) (i.e. 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid) by lipoxygenase, cyclooxygenase, and cytochrome P450 enzymes.
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