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Pages in category "CYP1A2 inhibitors" The following 15 pages are in this category, out of 15 total. This list may not reflect recent changes. A. Aciclovir ...
Following is a table of selected substrates, inducers and inhibitors of CYP1A2. Inhibitors of CYP1A2 can be classified by their potency, such as: Strong inhibitor being one that causes at least a 5-fold increase in the plasma AUC values of sensitive substrates metabolized through CYP1A2, or more than 80% decrease in clearance thereof. [18]
"INHIBITORS, INDUCERS AND SUBSTRATES OF CYTOCHROME P450 ISOZYMES". "The Life Raft Group: Long List of Inhibitors and Inducers of CYP3A4 and CYP2D6". "DRUGBANK Online: Cytochrome P-450 Enzyme Inhibitors". "MEDICATIONS METABOLIZED BY CYTOCHROME P450 3A4" (PDF)
Clozapine, imipramine, paracetamol, phenacetin Heterocyclic aryl amines Inducible and CYP1A2 5-10% deficient oxidize uroporphyrinogen to uroporphyrin (CYP1A2) in heme metabolism, but they may have additional undiscovered endogenous substrates. are inducible by some polycyclic hydrocarbons, some of which are found in cigarette smoke and charred ...
Cytochrome P450 inhibitors is a category of agents that inhibit Cytochrome ... CYP1A2 inhibitors (15 P) CYP2C8 inhibitors ... This list may not reflect recent changes. A.
ritonavir (Norvir): Inhibition of CYP3A4 prevents the metabolism of protease inhibitors such as ritonavir. [52] sertraline (Zoloft and Lustral) [53] verapamil (Covera-HS, Calan, Verelan, and Isoptin) [54] Drugs that interact with grapefruit compounds at CYP1A2 include caffeine [55] Drugs that interact with grapefruit compounds at CYP2D6 include
Monoamine oxidase inhibitors (MAOIs) have a long and prosperous history as medications for major depressive disorder (MDD). But this type of antidepressant has mostly seen its day. 4 FDA-Approved ...
Ciprofloxacin is weakly bound to serum proteins (20–40%). It is an inhibitor of the drug-metabolizing enzyme cytochrome P450 1A2, which leads to the potential for clinically important drug interactions with drugs metabolized by that enzyme. [5] Ciprofloxacin is about 70% available when administered orally. [3]
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