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Malathion is an acetylcholinesterase inhibitor, a diverse family of chemicals.Upon uptake into the target organism, it binds irreversibly to the serine residue in the active catalytic site of the cholinesterase enzyme.
As a result of cholinergic crisis, the muscles stop responding to the high synaptic levels of acetylcholine, leading to flaccid paralysis, respiratory failure, and other signs and symptoms reminiscent of organophosphate poisoning. Other symptoms include increased sweating, salivation, bronchial secretions along with miosis (constricted pupils).
The brain is more vulnerable to oxidative stress than other organs, due to its low oxidative capacity. Because neurons are characterized as postmitotic cells, meaning that they live with accumulated damage over the years, accumulation of ROS is fatal. Thus, increased levels of ROS age neurons, which leads to accelerated neurodegenerative ...
Common side effects include vomiting, black stools, diarrhea, and constipation. [1] A more serious side effect, pneumonitis, may result if aspirated into the lungs. [1] [2] Gastrointestinal obstruction and ileus are less common but serious adverse effects. [1] Use in pregnancy and breastfeeding is generally safe. [3]
Toxic encephalopathy is a neurologic disorder caused by exposure to neurotoxic organic solvents such as toluene, following exposure to heavy metals such as manganese, as a side effect of melarsoprol treatment for African trypanosomiasis, adverse effects to prescription drugs, or exposure to extreme concentrations of any natural toxin such as cyanotoxins found in shellfish or freshwater ...
Jamie Lynn Sigler Paul Archuleta/Getty Images Jamie-Lynn Sigler is sharing more details about the onset of her multiple sclerosis symptoms. During the Tuesday, May 7, episode of her and Christina ...
Extrapyramidal symptoms (EPS) are symptoms that are archetypically associated with the extrapyramidal system of the brain's cerebral cortex. When such symptoms are caused by medications or other drugs, they are also known as extrapyramidal side effects (EPSE). The symptoms can be acute (short-term) or chronic (long-term).
Well, according to Wise, the brain is actually the most powerful sex organ there is—namely because genital stimulation produces so much muscle and nerve information that a tremendous boost in ...