Search results
Results from the WOW.Com Content Network
Metformin is one of many medications that can cause lactic acidosis. Symptoms of lactic acidosis include nausea, vomiting and weakness. Fortunately, the risk of lactic acidosis is a rare side ...
Lactic acidosis can also be the result of illnesses, medications, poisonings or inborn errors of metabolism that interfere directly with oxygen utilization by cells. [ 1 ] The symptoms are generally attributable to the underlying cause, but may include nausea , vomiting , shortness of breath, and generalised weakness.
Given severely impaired kidney function, clearance of metformin and lactate is reduced, increasing levels of both, and possibly causing lactic acid buildup. Because metformin decreases liver uptake of lactate, any condition that may precipitate lactic acidosis is a contraindication.
The medication most commonly may cause stomach upset and symptoms such as diarrhea but in general is well tolerated and has a relatively low chance of causing hypoglycemia. [35] One rare (about 1% chance) but serious side affect of metformin is that it can cause lactic acidosis, usually in patients with poor kidney function. [35]
While rare, lactic acidosis (when lactic acid, the same thing that makes you sore after a workout, builds up in the blood) can be a side effect in those with poor kidney or liver function or due ...
It may be used in those whose blood sugar is not controlled with metformin and a sulfonylurea. [10] [11] It is taken by mouth. [10] Common side effects include diarrhea, headache, and upper respiratory tract infections. [5] Serious side effects may include lactic acidosis, pancreatitis, low blood sugar, heart failure, joint pain, and allergic ...
The variety of interactions makes cause identification difficult in many instances. It is more accurate to note that iatrogenic hypoglycemia is typically the result of the interplay of absolute (or relative) insulin excess and compromised glucose counterregulation in type 1 and advanced type 2 diabetes.
Higher risk of gastrointestinal side effects; Due to the risk of potentially fatal lactic acidosis, contraindicated in people with shock; with acute or chronic, moderate or severe kidney disease or at risk for impaired kidney function from intravenous dye; and with acute or chronic metabolic acidosis