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Lipohypertrophy [1] is a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin. It may be unsightly, mildly painful, and may change the timing or completeness of insulin action. It is a common, minor, chronic complication of diabetes mellitus.
“This is usually one of the first signs of diabetes,” Dr. Shafipour says. With diabetes, the body doesn’t make enough or any insulin, which is a hormone that helps to escort glucose (sugar ...
Injection site reactions (ISRs) are reactions that occur at the site of injection of a drug. They may be mild or severe and may or may not require medical intervention. Some reactions may appear immediately after injection, and some may be delayed. [1] Such reactions can occur with subcutaneous, intramuscular, or intravenous administration.
Insulin aspart, sold under the brand name Novolog, among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. [18] It is generally used by injection under the skin but may also be used by injection into a vein . [ 18 ]
Type 1 diabetes usually comes on abruptly, although the damage to the beta cells may begin much earlier. Typical signs of Type 1 diabetes are a great thirst, hunger, a need to urinate often, and loss of weight. To treat the disease, the person must inject insulin and test blood glucose frequently. [1]
The latest clinical trial results from Eli Lilly show the drug manufacturer's once-weekly insulin injection is just as effective as daily insulin shots for managing A1C levels in diabetes. Experts ...
One method of intensive insulinotherapy is based on multiple daily injections (sometimes referred to in medical literature as MDI). Meal insulin is supplied by injection of rapid-acting insulin before each meal in an amount proportional to the meal. Basal insulin is provided as a once or twice daily injection of dose of a long-acting insulin.
Most hypoglycemia due to excessive insulin occurs in people who take insulin for type 1 diabetes. Management of this hypoglycemia is sugar or starch by mouth (or in severe cases, an injection of glucagon or intravenous dextrose). When the glucose has been restored, recovery is usually complete.
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