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N-acetylphosphatidylethanolamine-hydrolysing phospholipase D (EC 3.1.4.54, NAPE-PLD, anandamide-generating phospholipase D, N-acyl phosphatidylethanolamine phospholipase D, NAPE-hydrolyzing phospholipase D) is an enzyme with systematic name N-acetylphosphatidylethanolamine phosphatidohydrolase. [1] [2] It catalyses the following chemical reaction
N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) is an enzyme that catalyzes the release of N-acylethanolamine (NAE) from N-acyl-phosphatidylethanolamine (NAPE). This is a major part of the process that converts ordinary lipids into chemical signals like anandamide and oleoylethanolamine .
A hydrophobic cavity in NAPE-PLD provides an entryway for the substrate NAPE into the active site, where a binuclear zinc center orchestrates its hydrolysis. Unexpectedly, the structure unveils bile acids bind the membrane enzyme, enhancing dimer assembly and enabling catalysis.
NAPE-PLD may refer to: N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D [ wikidata ] N-acyl phosphatidylethanolamine-specific phospholipase D , an enzyme
Mirth Connect is a cross-platform interface engine used in the healthcare industry that enables the management of information using bi-directional sending of many types of messages.
The scope of hospital medicine includes acute patient care, teaching, research, and executive leadership related to the delivery of hospital-based care. Hospital medicine, like emergency medicine , is a specialty organized around the location of care (the hospital), rather than an organ (like cardiology ), disease (like oncology ), or a patient ...
The hospital first opened its doors in 1958 when it replaced Parks Victory Memorial Hospital. It is a Level III adult trauma center . The medical center is the largest employer in Napa County.
Napa State Hospital is a psychiatric hospital in Napa, California, founded in 1875. It is located along California State Route 221, the Napa-Vallejo Highway, and is one of California's five state mental hospitals. Napa State Hospital holds civil and forensic mental patients in a sprawling 138-acre campus. According to a hospital spokesperson ...