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Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...
Chronic fatigue, a long-term state of physical or mental exhaustion, a symptom of many chronic illnesses and of idiopathic chronic fatigue Myalgic encephalomyelitis/chronic fatigue syndrome , a discrete chronic medical condition characterized by post-exertional malaise , symptoms of profound intensity including fatigue, pain, and cognitive ...
Prolonged fatigue is fatigue that persists for more than a month, and chronic fatigue is fatigue that lasts at least six consecutive months, which may be caused by a physical or psychological illness, or may be idiopathic (no known cause). [1] Chronic fatigue with a known cause is twice as common as idiopathic chronic fatigue. [6]
Many names have been proposed for the illness. The most commonly used are chronic fatigue syndrome, myalgic encephalomyelitis, and the umbrella term myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Reaching consensus on a name has been challenging because the cause and pathology remain unknown.
Lethargy is a state of tiredness, sleepiness, weariness, fatigue, sluggishness, or lack of energy. It can be accompanied by depression , decreased motivation, or apathy . Lethargy can be a normal response to inadequate sleep, overexertion, overworking, stress, lack of exercise, improper nutrition, drug abuse, boredom , or a symptom of an ...
The Canadian Consensus Criteria require "post exertional malaise and/or [post exertional] fatigue" instead. [21] [22] [23] [19] [24] On the other hand, the older Oxford Criteria lack any mention of PEM, [25] and the Fukuda Criteria consider it optional. Depending on the definition of ME/CFS used, PEM is present in 60 to 100% of ME/CFS patients. [6]
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Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.