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Some drugs developed that include metals interact directly with other metals already present in protein active sites, while other drugs can use metals to interact with amino acids with the highest reduction potential. [4] Figure 2. Structure of Cisplatin, a platinum coordination complex. Examples of metals used in treatment include:
Carboplatin, an example of a metallopharmaceutical. A metallopharmaceutical is a drug that contains a metal as an active ingredient. [1] [2] Most commonly metallopharmaceuticals are used as anticancer or antimicrobial agents. The efficiency of metallopharmaceuticals is crucially dependent on the respective trace metal binding forms. [3]
Applications of iron oxide nanoparticles include terabit magnetic storage devices, catalysis, sensors, superparamagnetic relaxometry, high-sensitivity biomolecular magnetic resonance imaging, magnetic particle imaging, magnetic fluid hyperthermia, separation of biomolecules, and targeted drug and gene delivery for medical diagnosis and ...
The medical uses of silver include its use in wound dressings, creams, and as an antibiotic coating on medical devices. [ 2 ] [ 3 ] [ 4 ] Wound dressings containing silver sulfadiazine or silver nanomaterials may be used to treat external infections.
The use of gold compounds has decreased since the 1980s because of numerous side effects and monitoring requirements, limited efficacy, and very slow onset of action. Most chemical compounds of gold, including some of the drugs discussed below, are not salts, but are examples of metal thiolate complexes.
In biology and medicine, nitric oxide is however an important signalling molecule in nature and this fact is the basis of the most important applications of metal nitrosyls. The nitroprusside anion, [Fe(CN) 5 NO] 2− , a mixed nitrosyl cyano complex, has pharmaceutical applications as a slow release agent for NO.
Pages in category "Metal-containing drugs" The following 8 pages are in this category, out of 8 total. This list may not reflect recent changes. A. Auranofin;
Iron(III) oxide is also used as a pigment, under names "Pigment Brown 6", "Pigment Brown 7", and "Pigment Red 101". [22] Some of them, e.g., Pigment Red 101 and Pigment Brown 6, are approved by the US Food and Drug Administration (FDA) for use in cosmetics. Iron oxides are used as pigments in dental composites alongside titanium oxides. [23]