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Benedict's reagent is a deep-blue aqueous solution. Each litre contains: [4] 17.3 g copper sulfate; 173 g sodium citrate; 100 g anhydrous sodium carbonate or, equivalently, 270 g sodium carbonate decahydrate
Copper toxicity (or Copperiedus) is a type of metal poisoning caused by an excess of copper in the body. Copperiedus could occur from consuming excess copper salts, but most commonly it is the result of the genetic condition Wilson's disease and Menke's disease, which are associated with mismanaged transport and storage of copper ions.
Copper(II) sulfate is an inorganic compound with the chemical formula Cu SO 4.It forms hydrates CuSO 4 ·nH 2 O, where n can range from 1 to 7. The pentahydrate (n = 5), a bright blue crystal, is the most commonly encountered hydrate of copper(II) sulfate, [10] while its anhydrous form is white. [11]
Most of the copper (70 – 95%) excreted by the liver is incorporated into ceruloplasmin, the main copper carrier in blood. Copper is transported to extra-hepatic tissues by ceruloplasmin, [50] albumin and amino acids, or excreted into the bile. [19] By regulating copper release, the liver exerts homeostatic control over extra-hepatic copper. [22]
The water-soluble BCA/copper complex absorbs much more strongly than the peptide/copper complex, increasing the sensitivity of the biuret test by a factor of around 100: the BCA assay allows to detect proteins in the range of 0.0005 to 2 mg/mL.
Fehling's solution is prepared by combining two separate solutions: Fehling's A, which is a deep blue aqueous solution of copper(II) sulfate, and Fehling's B, which is a colorless solution of aqueous potassium sodium tartrate (also known as Rochelle salt) made strongly alkaline with sodium hydroxide. These two solutions, stable separately, are ...
Under these conditions, copper participates in the so-called Fenton-type reaction — a chemical reaction causing oxidative damage to cells. Excess copper causes a decline in the membrane integrity of microbes, leading to leakage of specific essential cell nutrients, such as potassium and glutamate. This leads to desiccation and subsequent cell ...
No totally reliable test for Wilson's disease is known, but levels of ceruloplasmin and copper in the blood, as well of the amount of copper excreted in urine during a 24-hour period, are together used to form an impression of the amount of copper in the body. The most accurate test is a liver biopsy. [5]