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The gene for LAMP2 has 9 coding exons and 2 alternate last exons, 9a and 9b. [6] When the last exon is spliced with the alternative exon, it is a variant called LAMP2b, which varies in the last 11 amino acids of its C-terminal sequence: in the luminal domain, the transmembrane domain, and the cytoplasmic tail.
A light combat aircraft (LCA) is a light, multirole jet/turboprop military aircraft, commonly derived from advanced trainer designs, designed for engaging in light combat. [ citation needed ] The mission can either be in a light strike or attack missions , reconnaissance , interdiction roles or trainer roles and even air-to-air fight.
Structurally, the lamp proteins consist of two internally homologous lysosome-luminal domains separated by a proline-rich hinge region; at the C-terminal extremity there is a transmembrane region (TM) followed by a very short cytoplasmic tail (C). In each of the duplicated domains, there are two conserved disulfide bonds. This structure is ...
HAL Tejas This is a timeline of the development of the HAL Tejas, a light-weight, multirole fighter aircraft manufactured by Hindustan Aeronautics Limited. 1980s 1983 The DRDO obtains permission to initiate a programme to design and develop a light combat aircraft. 1984 Government of India set up Aeronautical Development Agency (ADA) in 1984 as the nodal agency for managing and developing the ...
The LCA was the most common British and Commonwealth landing craft of World War II. [1] [2] Prior to July 1942, these craft were referred to as "assault landing craft" (ALC), but "landing craft, assault" (LCA) was used thereafter to conform with the joint US-UK nomenclature system. [3]
The other two isoforms LAMP-2B and LAMP-2C are involved in macroautophagy and vesicular trafficking, respectively. Substrate proteins undergo unfolding after binding to LAMP-2A in a process likely mediated by the membrane associated hsc70 and its co-chaperones Bag1, hip, hop and hsp40, also detected at the lysosomal membrane. [ 8 ]
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LCA MMR - 3D advanced, ... In service in many US Navy ships as well as in the SH-2F LAMPS I ASW helicopter. [citation needed] AN/SPS-60 Solid state version of AN/APS-53.