Search results
Results from the WOW.Com Content Network
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Pages for logged out editors learn more
Statins with shorter half-lives are more effective when taken in the evening, so their peak effect occurs when the body's natural cholesterol production is at its highest. A recent meta-analysis suggested that statins with longer half-lives, including atorvastatin, may also be more effective at lowering LDL cholesterol if taken in the evening. [38]
Statins are usually used to lower blood cholesterol levels and reduce risk for illnesses related to atherosclerosis, with a varying degree of effect depending on underlying risk factors and history of cardiovascular disease. [16]
Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries.This is a chronic inflammatory disease involving many different cell types and driven by elevated levels of cholesterol in the blood. [9]
The drug was billed as a "super-statin" during its clinical development; the claim was that it offered high potency and improved cholesterol reduction compared to rivals in the class. The main competitors to rosuvastatin are atorvastatin and simvastatin.
Get the Boydton, VA local weather forecast by the hour and the next 10 days.
The first statin drug available to the general public was lovastatin. Mevastatin has since been derivatized to the compound pravastatin , which is a pharmaceutical used in the lowering of cholesterol and preventing cardiovascular disease .
It is characterised by progressive muscle wasting which affects predominantly hip and shoulder muscles. [8] LGMD usually has an autosomal pattern of inheritance. It currently has no known cure or treatment. [3] [9] LGMD may be triggered or worsened in genetically susceptible individuals by statins, because of their effects on HMG-CoA reductase ...