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  2. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    A low red blood cell count . [10] [4] [2] [12] These symptoms may worsen over time. [8] [2] While the exact cause of CLL is unknown, having a family member with CLL increases one's risk of developing the disease. [10] [4] Environmental risk factors include exposure to Agent Orange, ionizing radiation, and certain insecticides.

  3. Thrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Thrombocytopenia

    Laboratory tests for thrombocytopenia might include full blood count, liver enzymes, kidney function, vitamin B 12 levels, folic acid levels, erythrocyte sedimentation rate, and peripheral blood smear. If the cause for the low platelet count remains unclear, a bone marrow biopsy is usually recommended to differentiate cases of decreased ...

  4. Pseudothrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Pseudothrombocytopenia

    Pseudothrombocytopenia (PTCP) or spurious thrombocytopenia is an in-vitro sampling problem which may mislead the diagnosis towards the more critical condition of thrombocytopenia. The phenomenon may occur when the anticoagulant used while testing the blood sample causes clumping of platelets which mimics a low platelet count. [1]

  5. Richter's transformation - Wikipedia

    en.wikipedia.org/wiki/Richter's_transformation

    Individuals with CLL/SLL are considered to be at an increased risk for developing RT if they have: 1) enlarged lymph nodes, liver, and/or spleen; 2) advanced stage disease; 3) low blood platelet counts and/or elevated serum beta-2-microglobulin levels; 4) CLL/SLL cells which develop deletions in the CDKN2A gene, disruptions of the TP53 gene ...

  6. Pancytopenia - Wikipedia

    en.wikipedia.org/wiki/Pancytopenia

    Pancytopenia is a medical condition in which there is significant reduction in the number of almost all blood cells (red blood cells, white blood cells, platelets, monocytes, lymphocytes, etc.). If only two parameters from the complete blood count are low, the term bicytopenia can be used. The diagnostic approach is the same as for pancytopenia.

  7. Monoclonal B-cell lymphocytosis - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_B-cell_lymphocy...

    The key factor that distinguishes low-count CLL/SLL-MLB, high-count CLL/SLL-MLB, and CLL/SLL is the number of circulating monoclonal B cells, as described above. However, the other MLB phenotypes may progress to and/or be mimicked by various monoclonal B-cell lymphocyte malignancies.

  8. Thrombocythemia - Wikipedia

    en.wikipedia.org/wiki/Thrombocythemia

    When the cause is known such as another disorder or disease, the term thrombocytosis is preferred, as either secondary or reactive thrombocytosis. Reactive thrombocytosis is the most common type and though it can often have no symptoms it can sometimes predispose to thrombosis. In contrast, thrombocytopenia refers to abnormally low blood ...

  9. Autoimmune hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_hemolytic_anemia

    Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder which occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst , leading to an insufficient number of oxygen-carrying red blood cells in circulation . The lifetime of the RBCs is reduced from the normal 100–120 days to just a few days in ...

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