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The gastroduodenal artery can be the source of a significant gastrointestinal bleed, which may arise as a complication of peptic ulcer disease.Because of its close relationship to the posteromedial wall of the second part of the duodenum, deeply penetrating ulcers or tumours of the duodenum may cause torrential bleeding from the gastroduodenal ‘artery of haemorrhage'. [1]
Posterior gastric wall perforation may lead to bleeding due to the involvement of gastroduodenal artery that lies posterior to the first part of the duodenum. [22] The death rate in this case is 20%. [15] Penetration is a form of perforation in which the hole leads to and the ulcer continues into adjacent organs such as the liver and pancreas. [16]
The reason for that is explained by their location. The peritoneal or abdominal cavity is located anterior to the duodenum. Therefore, if the ulcer grows deep enough, it will perforate, whereas if a posterior ulcer grows deep enough, it will penetrate the gastroduodenal artery and bleed. [citation needed]
Endoscopic image of a posterior wall duodenal ulcer with a clean base, which is a common cause of upper gastrointestinal hemorrhage. Specialty: Gastroenterology: Symptoms: Hematemesis (vomiting blood), coffee ground vomiting, melena, hematochezia (maroon-coloured stool) in severe cases
About half of cases are due to peptic ulcer disease (gastric or duodenal ulcers). [3] Esophageal inflammation and erosive disease are the next most common causes. [3] In those with liver cirrhosis, 50–60% of bleeding is due to esophageal varices. [3] Approximately half of those with peptic ulcers have an H. pylori infection. [3]
The transition between these sources is important as it demarcates the foregut from the midgut. Proximal to the 2nd part of the duodenum (approximately at the major duodenal papilla – where the bile duct enters) the arterial supply is from the gastroduodenal artery and its branch the superior pancreaticoduodenal artery.
A stress ulcer is a single or multiple ... injurious effects of acid and pepsin on the gastroduodenal mucosa. ... into the left gastric artery may help control the ...
A peptic ulcer is a defect in the inner lining of the stomach or duodenum typically due to excessive stomach acid. Extension of the ulcer through the lining of the digestive tract results in spillage of the stomach or intestinal contents into the abdominal cavity, leading to an acute chemical peritonitis.